Yes and no.
In this configuration it is an easy “drop in” replacement. Just swapping out the Z axis using the same stock mounting holes in the gantry plate. But it can not be mounted in reverse.
You can reverse it, and the c-beam style CNC do so, but it requires modifying / replacing the gantry plate(s). I am in the process of doing this myself, replacing both the Z and X axis with C-Beams: Gantry Upgrade to C-Beam