Airflow is the key. I have this thing:
It is hooked up to a separate regulator that is mounted to the CNC table so I can control the air pressure from the CNC table. I normally run it between 15-20 PSI. It runs the entire time I am cutting any material that isn’t wood.
Yes it makes a huge mess. In my shop, it is not a big deal.
I have cut both cast and extruded acrylic with zero issues. I used the 3.175mm 2 flute bit. Dewalt 611. Feed - 2000 mm/min
Speed - 1
Depth - .25mm
Here is an edge lit cast acrylic cut:
And here is a back lit extruded acrylic cut. For this one, each color is cut .25mm deeper than the previous color. Darkest colors were cut first then lighter colors ending with white.
The key is the air. You have to get the chips out of there right away or they will melt and gum up the bit. I ran an airhose through the drag chains and I have the loc-line mounted right to spindle mount. Then the nozzle itself is positioned to blow right where the bit is cutting.