If you have homing switches turned on and enabled, you can set repeatable, recallable workpiece home positions. I made a forum post about using multiple home positions and some of the advanced features of it here.
I use UGS as my G Code sender, but did the initial machine setup using the Easel machine setup. It prompted me to choose whether or not my machine had limit switches installed or not. How I just use $H to home the machine in UGS.